Oftoxane Drops

Antiallergic – Decongestant – Anti-inflammatory – Antibiotic. antipruritic and analgesic

Formula | Every 100 ml contains:
Gentamicin Sulfate …………………………. 300 mg
Naphazoline hydrochloride ……………… 50 mg
Dexamethasone 21 phosphate ………….. 100 mg
Benzalkonium chloride …………………….  0.01 gr
Distilled water q.s. …………………………… 100 ml

Pharmacological properties
This is a topical product.
Gentamicin acts on susceptible bacteria by binding irreversibly to 30S ribosomal unit which inhibits protein synthesis, it is recommended as a therapy in gram-negative bacteria infections. Naphazoline is a vasoconstrictor that serves as a symptomatic treatment of conjunctival hyperemia. Dexamethasone is used both to treat inflammations as intraocular surface

Indications
Anti-allergic eye drops – Decongestant – Anti-inflammatory – Antibiotic. antipruritic and analgesic.
Eye diseases in general for the treatment of ocular lesions caused by Infectious Keratoconjunctivitis and other non-specific conjunctivitis, blepharitis, keratitis and ocular lesions in general.
Corneal infections, gram-negative or staphylococcal. Topical dexamethasone to treat inflammation of the surface or anterior segment

Contraindications
Known hypersensitivity to any component of the formula, Glaucoma.

Special warnings and precautions
OFTOXANE is packaged under sterile conditions. To prevent contamination must be careful not to touch eyelids, eyelashes and adjacent areas or any other surface with the tip of the bottle. Keep the dropper bottle and bottle dispenser carefully closed.

PRECAUTIONS
As with other antibiotics, prolonged use may result in overgrowth of non-susceptible organisms, including fungi. It is recommended to periodically examine the patient. It should discontinue use of the product at the first sign of rash or other hypersensitivity reaction.
It should be considered that persistent corneal fungal infections after prolonged treatment with corticosteroids may happen. Prolonged use of dexamethasone can result in lens opacity (cataract), increased intraocular pressure in susceptible patients and secondary infections.
The owners of the animals should be instructed to properly handle the peak of the bottle avoiding contact with the eye and adjacent structures or any other surface. Animal owners should be informed that the inappropriate handling of the bottle can contaminate causing eye infections. The use of contaminated products may cause serious eye damage.

ADVERSE REACTIONS
Adverse reactions have been reported rarely occur with drugs that associate a steroid and an anti-infective agent, which can be attributed to the steroid component, the anti-infective component, or the combination of both. Hypersensitivity and localized ocular toxicity (itching and swelling and conjunctival erythema Eyelid rarely occur). The most common adverse reaction was burning or local discomfort.
The reactions due to the steroid component are: intraocular hypertension.

DOSAGE AND DOSAGE
Dose for sheep, horses and cattle: Spray the injured tissues and surrounding areas. Spray the affected eye every 8 hours for 3 days or according to the criteria of the veterinarian.
In canines and felines: 2 to 3 drops in each affected eye three times a day.
Interval between doses: 3 days or according to criteria of the veterinarian.

PRESENTATION:
Sterile solution in dropper bottle with inviolable screw cap. Bottle containing 5, 10, 15 and 30 ml of solution, prospectus and box.
PET bottle containing atomizing valve 30, 60, 100, 250 and 500 ml

Storage
Store at temperature below 35 ° C.
Once broached for the first time, use it within 4 weeks.
Keep medicines out of reach of children.

Antiallergic – Decongestant – Anti-inflammatory – Antibiotic. antipruritic and analgesic

Formula | Every 100 ml contains:
Gentamicin Sulfate …………………………. 300 mg
Naphazoline hydrochloride ……………… 50 mg
Dexamethasone 21 phosphate ………….. 100 mg
Benzalkonium chloride …………………….  0.01 gr
Distilled water q.s. …………………………… 100 ml

Pharmacological properties
This is a topical product.
Gentamicin acts on susceptible bacteria by binding irreversibly to 30S ribosomal unit which inhibits protein synthesis, it is recommended as a therapy in gram-negative bacteria infections. Naphazoline is a vasoconstrictor that serves as a symptomatic treatment of conjunctival hyperemia. Dexamethasone is used both to treat inflammations as intraocular surface

Indications
Anti-allergic eye drops – Decongestant – Anti-inflammatory – Antibiotic. antipruritic and analgesic.
Eye diseases in general for the treatment of ocular lesions caused by Infectious Keratoconjunctivitis and other non-specific conjunctivitis, blepharitis, keratitis and ocular lesions in general.
Corneal infections, gram-negative or staphylococcal. Topical dexamethasone to treat inflammation of the surface or anterior segment

Contraindications
Known hypersensitivity to any component of the formula, Glaucoma.

Special warnings and precautions
OFTOXANE is packaged under sterile conditions. To prevent contamination must be careful not to touch eyelids, eyelashes and adjacent areas or any other surface with the tip of the bottle. Keep the dropper bottle and bottle dispenser carefully closed.

PRECAUTIONS
As with other antibiotics, prolonged use may result in overgrowth of non-susceptible organisms, including fungi. It is recommended to periodically examine the patient. It should discontinue use of the product at the first sign of rash or other hypersensitivity reaction.
It should be considered that persistent corneal fungal infections after prolonged treatment with corticosteroids may happen. Prolonged use of dexamethasone can result in lens opacity (cataract), increased intraocular pressure in susceptible patients and secondary infections.
The owners of the animals should be instructed to properly handle the peak of the bottle avoiding contact with the eye and adjacent structures or any other surface. Animal owners should be informed that the inappropriate handling of the bottle can contaminate causing eye infections. The use of contaminated products may cause serious eye damage.

ADVERSE REACTIONS
Adverse reactions have been reported rarely occur with drugs that associate a steroid and an anti-infective agent, which can be attributed to the steroid component, the anti-infective component, or the combination of both. Hypersensitivity and localized ocular toxicity (itching and swelling and conjunctival erythema Eyelid rarely occur). The most common adverse reaction was burning or local discomfort.
The reactions due to the steroid component are: intraocular hypertension.

DOSAGE AND DOSAGE
Dose for sheep, horses and cattle: Spray the injured tissues and surrounding areas. Spray the affected eye every 8 hours for 3 days or according to the criteria of the veterinarian.
In canines and felines: 2 to 3 drops in each affected eye three times a day.
Interval between doses: 3 days or according to criteria of the veterinarian.

PRESENTATION:
Sterile solution in dropper bottle with inviolable screw cap. Bottle containing 5, 10, 15 and 30 ml of solution, prospectus and box.
PET bottle containing atomizing valve 30, 60, 100, 250 and 500 ml

Storage
Store at temperature below 35 ° C.
Once broached for the first time, use it within 4 weeks.
Keep medicines out of reach of children.

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